The power and promise of Genome-WIDE ASSOCIATION studies

Posted on 26 July, 2017 by Carlo Pecoraro

 

The genetic sources of phenotypic variation have been a major focus of both plant and animal studies aimed at identifying the causes of disease, improving agriculture and understanding adaptive processes. To address those questions, genome-wide association studies (GWAS) emerged through the recent advent of next-generation sequencing (NGS) technologies. This approach searches for hundreds or thousands of SNPs across the genome to survey the most common genetic variation for a role in a disease or to identify the heritable quantitative traits that are risk factors for diseases. Continue reading

 

Visualizing genomic data: techniques and challenges.

Posted on 27 June, 2017 by Carlo Pecoraro

 

The advent of Next Generation Sequencing technologies has allowed the rapid production of massive amounts of genomic data, and created a corresponding need for new tools and methods for visualizing and interpreting these data in order to extract relevant biological information. Continue reading

 

R without fear

Posted on 18 May, 2017 by Carlo Pecoraro

At the R Project  website, R is defined as a free software environment for statistical computing and graphics. It compiles and runs on a wide variety of UNIX platforms, Windows and MacOS. Continue reading

 

RNA-seq data analysis

Posted on 08 March, 2017 by Marianna Pauletto

 

RNA-Seq (RNA sequencing), has revolutionized the manner in which eukaryotic transcriptomes are analysed, at an unprecedented scale and speed, even in non-model organisms.  Continue reading

Switching from population genetics to Population genomics

Posted on 25 February, 2017 by Carlo Pecoraro

 

The term ‘population genomics’ started to appear in the literature from the late 1990s, mainly in the context of large-scale polymorphism analyses in humans. Continue reading

Want to learn more about data visualization with Python?

Posted on 10 January, 2017 by Carlo Pecoraro

 

 

Data visualization is an important part of being able to explore data and communicate results. Continue reading

Q&A: Dr. Martin Jones helps us understand the importance of learning Linux and Python.

Posted on 05 September, 2016 by Carlo Pecoraro

 

The need for Bioinformatics skills has increased and become unconditionally fundamental for experimentalists to acquire at least basic skills to enquiry, retrieve and handle the biological information that is regularly accumulating in various databases. Continue reading