21-25 September 2020
General Topic: Comparative genomics with a focus on structural variation
This course will introduce biologists and bioinformaticians into the field of comparative genomics. We will cover a broad range of software and analysis workflows that extend over the spectrum from assembling and annotating small eukaryotic genomes, via the identification of single nucleotide variants (SNVs) and structural variants (SVs) within the population, to the assessment of their likely functional impact of the detected variants in an evolutionary context.
The course is structured in modules over five days. Each day will include an introductory lecture with class discussion of key concepts. The remainder of each day will consist of practical hands-on sessions. These sessions will involve a combination of both mirroring exercises with the instructor to demonstrate a skill as well as applying these skills on your own to complete individual exercises. After and during each exercise, interpretation of results will be discussed as a group.